Physical Examination 
• Jaundice .
• Abdominal masses. 
• Enlarged gallbladder—50 percent of cases (carcinoma of head of pancreas).
• Enlarged liver (hepatomegaly). 
• Abdominal fluid (ascites). 
• Enlarged lymph nodes . 
• Phlebitis (swollen legs).

Blood and Other Tests 
• Complete blood count (CBC) and platelet count.
• The carcinoembryonic antigen (CEA) is elevated in 50 percent of cases.
• CA 19-9 is elevated in 70 to 80 percent of pancreatic cancer cases and is a better test than the CEA because it
  is 87 percent specific. (In many cases of pancreatic cancer, both the CEA and the CA 19-9 are elevated.)
• Serum bilirubin is elevated in patients with bile duct obstruction.
• Serum alkaline phosphatase will be elevated if there are liver or bone metastases or if there is bile duct
  obstruction.